Intracellular delivery of biomineralized monoclonal antibodies to combat viral infection.

نویسندگان

  • Zhiyong Song
  • Long Liu
  • Xiaoyu Wang
  • Yongqiang Deng
  • Qinggong Nian
  • Guangchuan Wang
  • Shunya Zhu
  • Xiaofeng Li
  • Hangyu Zhou
  • Tao Jiang
  • Xurong Xu
  • Ruikang Tang
  • Chengfeng Qin
چکیده

Conventional therapeutic monoclonal antibodies (mAbs) are invalid for intracellular viruses but by using in situ biomineralization treatment, they can be successfully delivered into cells to inhibit intracellular viral replication. This achievement significantly expands the applications of mAbs and provides a new intracellular strategy to control viral infections.

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عنوان ژورنال:
  • Chemical communications

دوره 52 9  شماره 

صفحات  -

تاریخ انتشار 2016